Anzctr MCP Server

@pipeworx/anzctr

Australian New Zealand Clinical Trials Registry (ANZCTR, anzctr.org.au): the full registered record for one trial by ACTRN. ANZCTR is the WHO primary registry for Australia and New Zealand, and many of its trials are not on ClinicalTrials.gov.

Part of Pipeworx — an MCP gateway connecting AI agents to 1861+ live data sources. This is an independent, unofficial integration — not affiliated with, endorsed by, or published by the upstream provider.

Tools

• anzctr_trial({actrn}) — the full record for one trial: titles, status, phase and design, health conditions and condition codes, intervention and comparator, primary and secondary outcomes, eligibility, target sample size, key dates, primary sponsor, funding sources, ethics committees, secondary IDs. An ACTRN with no public record returns found: false. Every response carries data_as_of (the time the registry was read).

Use alongside clinicaltrials (US registry) and isrctn (UK/international).

Searching ANZCTR: use ictrp_search

To find ANZCTR trials, call ictrp_search({query, registry: "ANZCTR"}) from the who-ictrp pack. WHO ICTRP indexes every ANZCTR record and is not behind ANZCTR's Cloudflare challenge. Verified through the live gateway on 2026-10-09: {query: "psilocybin", registry: "ANZCTR"} returned ACTRN rows such as ACTRN12626001100381, and anzctr_trial on that id returned the full record. ICTRP refreshes from the registries weekly, so a trial registered in the last few days may only be reachable by ACTRN here.

Why there is no anzctr_search

ANZCTR's search (TrialSearch.aspx) is an ASP.NET WebForms postback. A working implementation exists in commit f1c44beb0 (anzctr_search: GET the form for its __VIEWSTATE and session cookie, POST it back with ctl00$body$searchTxtBx, interventionDescriptionTxtBx, healthConditionTxtBx, registryRdBtnLst=ANZCTR and the btnSearch button). On 2026-10-09 it returned 45 psilocybin records from a throwaway Worker on our Cloudflare account, but every call from the live gateway got a Cloudflare Managed Challenge (HTTP 403, "I'm Under Attack Mode - The University of Sydney") on TrialSearch.aspx, while the record page answered normally. A laptop is challenged on the search page too. The egress relay (supabase/functions/egress-proxy) does not carry cookies, which the postback needs. Fleet #2897 closed on the ictrp_search route above; a direct anzctr_search is only worth reviving if ICTRP's weekly lag becomes the complaint.

Auth

Keyless.

Data sources

• https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12626001215314 — the public record page for one trial.

ANZCTR has no JSON API; the record page is HTML with one <span id="ctl00_body_CX…"> per field and ctl00_body_repeater_TX…_ctlNN_CX… spans for repeated rows (conditions, outcomes, funders).

Things the next person would otherwise rediscover:

• Some ACTRNs carry a trailing letter (ACTRN12626001117303p); the record page takes the 14 digits alone, and so does the tool.
• The record page is answered from the live gateway and from a laptop; only TrialSearch.aspx is challenged.
• An unknown ACTRN 302s to /Notification.aspx.
• Records include contact persons with names, phone numbers and email addresses. The tool does not return them.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "anzctr": {
      "url": "https://gateway.pipeworx.io/anzctr/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/anzctr/mcp returns the tools in the table above plus the shared Pipeworx meta-tools — ask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1861+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

No MCP client? Call it over HTTP

curl -X POST https://gateway.pipeworx.io/v1/tools/anzctr_trial \
  -H 'Content-Type: application/json' \
  -d '{"actrn":"ACTRN12626001215314"}'

No account needed for the first calls. Inspect any tool: GET https://gateway.pipeworx.io/v1/tools/anzctr_trial. Find one: POST https://gateway.pipeworx.io/v1/tools/search_packs with {"query":"..."}.

Run it from npm

@pipeworx/mcp-anzctr is a local stdio bridge to the Pipeworx gateway: your MCP client starts it with npx, and it forwards every call to the same https://gateway.pipeworx.io/anzctr/mcp endpoint shown above. It needs network access; there is no offline mode.

{
  "mcpServers": {
    "anzctr": {
      "command": "npx",
      "args": ["-y", "@pipeworx/mcp-anzctr"]
    }
  }
}

Without a key it calls anonymously, capped at 50 calls a day. A free account raises that to 200 a day: get a key at https://pipeworx.io/signup and add "env": { "PIPEWORX_API_KEY": "<your key>" } to the server entry. The key is sent as a Bearer token, the same way a hosted connection sends it, so calls are metered and billed exactly as they are there.

It lists only this pack's tools by default. Set PIPEWORX_META_TOOLS=1 to also list ask_pipeworx and the other gateway-wide tools.

Behind an HTTPS proxy: Node's built-in fetch does not read HTTPS_PROXY by default. Newer Node releases honour it when NODE_USE_ENV_PROXY=1 is set; check your Node version's documentation.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Anzctr data" })

The gateway picks the right tool and fills the arguments automatically.

More

• Docs and guides
• pipeworx.io

License

MIT