Question 1

What does Pubchem do?

Accepted Answer

Search PubChem compounds, properties, safety data, bioactivity, and cross-references.

Remote endpoints:
streamable-http: https://pubchem.caseyjhand.com/mcp

Question 2

Is Pubchem free?

Accepted Answer

Yes, Pubchem is free to use.

Question 3

How do I install Pubchem?

Accepted Answer

Pubchem supports both local and remote installation. For local use, install it via npm (npx) and add the configuration to your AI app. For remote access, add the server URL to your MCP configuration.

Question 4

Is Pubchem safe to use?

Accepted Answer

Yes. Pubchem passed MCP Marketplace's automated security scan with a score of 10/10 (low risk). Every server on MCP Marketplace is security-scanned before it's listed; see the full security report on this page for the findings and permissions.

Question 5

What credentials does Pubchem need?

Accepted Answer

Pubchem requires the following credentials or environment variables: MCP_LOG_LEVEL, MCP_HTTP_HOST, MCP_HTTP_PORT, MCP_HTTP_ENDPOINT_PATH, MCP_AUTH_MODE. You can find setup instructions on the server detail page.

Question 6

What AI apps work with Pubchem?

Accepted Answer

Pubchem uses the Model Context Protocol (MCP) and works with any MCP-compatible AI app, including Claude, ChatGPT / Codex, Gemini, Copilot, Cursor, and more.

Pubchem MCP Server

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